ME Seminar Series: Multiplexed Electrosprays: Principles and Applications

Oct 1

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Monday, October 1, 2012 - 3:00pm to 4:15pm

The cone-jet electrospray has revolutionized the field of mass spectrometry but, despite the unique ability of this device to produce quasi-monodispersed particles in a phenomenal size range, it has not been applied to other fields. The low flow rate at which the spray is dispersed is primary reason for the lack of widespread use. Compact multiplexing, that is, with a high number of sources per unit area, is indispensable for dramatically increasing the throughput and reducing the cost per electrospray source. Using microfabrication we recently demonstrated successful operation of multiplexed electrospray systems with an unprecedented packing density of up to 11,547 sources/cm2. In this seminar, I will review fluid mechanical and electrostatic criteria for successful multiplexing and describe some diverse applications in which we successfully tested this device, including: polymer particle synthesis for controlled drug delivery, microchip cooling and electric propulsion.